Varenicline N-oxide (Mono TFA Salt) is an impurity present in Varenicline, varenicline was developed to work specifically on the factors that underlie nicotine addiction. which has Phase II and Phase III trials established dosing safety profiles and efficacy, which is safe and effective in treating tobacco dependence in people who are at higher chance for neuropsychiatric symptoms and cardiovascular disease.
References
Ebbert, J., Burke, M. V., & Hays, J. T. (2016). Varenicline for smoking cessation: a narrative review of efficacy, adverse effects, use in at-risk populations, and adherence. Patient Preference and Adherence, 435. https://doi.org/10.2147/ppa.s83469
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