Amantadine Impurities

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Parent Drug Name Name of Impurity Catalogue No.
Amantadine Amantadine EP Impurity A VL2290007View CAS 935-56-8
Amantadine Amantadine EP Impurity B VL2290008View CAS 880-52-4
Amantadine Amantadine Impurity 2 VL2290001View CAS 702-77-2
Amantadine Amantadine Impurity 3 VL2290002View CAS 878-61-5

Amantadine Related Compound

Amantadine is an antidyskinetic drug. It is used to treat Parkinson’s disease and related symptoms, such as dyskinetic (also known as “paralysis agitates” or “shaking palsy”) (sudden uncontrolled movements). It can be used either on its own or in conjunction with other Parkinson’s disease medications (such as levodopa).

References

  • Amantadine: MedlinePlus Drug Information.” Medlineplus.gov, 2021, medlineplus.gov/druginfo/meds/a682064.html#:~:text=Amantadine%20is%20in%20a%20class,certain%20parts%20of%20the%20body. Accessed 20 Feb. 2023.
  • Hosenbocus, Sheik, and Raj Chahal. “Amantadine: A Review of Use in Child and Adolescent Psychiatry.” Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l’Academie Canadienne de Psychiatrie de l’Enfant et de L’adolescent, vol. 22, no. 1, 2013, pp. 55–60, www.ncbi.nlm.nih.gov/pmc/articles/PMC3565716/#:~:text=Amantadine%20has%20been%20used%20successfully,dysfunction%20described%20in%20these%20disorders. Accessed 20 Feb. 2023.
  • Krzystanek, Marek, et al. “Amantadine in the Treatment of Sexual Inactivity in Schizophrenia Patients Taking Atypical Antipsychotics—the Pilot Case Series Study.” Pharmaceuticals, vol. 14, no. 10, Sept. 2021, p. 947, https://doi.org/10.3390/ph14100947. Accessed 20 Feb. 2023.

FAQ

What therapeutic group does amantadine belong to?

Amantadine belongs to the group of drugs known as Amantadine. It’s supposed to improve mobility issues by boosting dopamine levels in specific areas of the body.

What is amantadine used for in psychiatry?

Due to the glutamatergic dysfunction reported in resistant unipolar depression and obsessive-compulsive disorder, amantadine has been utilized successfully as an augmenting drug in both conditions.

Is amantadine used for schizophrenia?

Amantadine is another therapeutic option for the management of sexual dysfunction in schizophrenic patients. It has long been used for this purpose to address the negative effects of antipsychotic medication such as hyperprolactinemia and sexual dysfunction.

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702-77-2: Amantadine Impurity 2

702-77-2: Amantadine Impurity 2
Catalogue No.

VL2290001

CAS No.

702-77-2

Molecular Formula

C11H17Br

Molecular Weight

229.16

Parent drug

Amantadine

IUPAC Name

1-Methyl-3-bromoadamantane

Synonyms

N/A

References

Status

In-stock

ListName

Amantadine Impurity 2

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