Anastrozole Impurities

Anastrozole is a hormonal therapy.

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Parent Drug Name Name of Impurity Catalogue No.
Anastrozole Anastrozole 1, 3-Dibromomethyl Impurity VL2490014View CAS 19294-04-3
Anastrozole Anastrozole 1, 3-Dicyanomethyl Impurity VL2490009View CAS 120511-74-2
Anastrozole Anastrozole Amide Nitrile VL2490023View CAS 120512-03-0
Anastrozole Anastrozole Diacid VL2490004View CAS 1338800-81-9
Anastrozole Anastrozole Diamide Impurity VL2490003View CAS 120512-04-1
Anastrozole Anastrozole EP Impurity A VL2490001View CAS 1215780-15-6
Anastrozole Anastrozole EP Impurity B VL2490006View CAS 1216898-82-6
Anastrozole Anastrozole EP Impurity C VL2490007View CAS 120511-84-4
Anastrozole Anastrozole EP Impurity D VL2490008View CAS 1027160-12-8
Anastrozole Anastrozole EP Impurity E VL2490012View CAS 120511-88-8
Anastrozole Anastrozole EP Impurity G VL2490011View CAS 120511-92-4
Anastrozole Anastrozole EP Impurity H VL2490010View CAS 120511-72-0
Anastrozole Anastrozole EP Impurity I VL2490013View CAS 120511-91-3
Anastrozole Anastrozole Formyl Impurity VL2490027View CAS 120511-89-9
Anastrozole Anastrozole Impurity 15 VE0012228View CAS 2447054-72-8
Anastrozole Anastrozole Impurity A VE0012229View CAS 918312-71-7
Anastrozole Anastrozole Monoacid Monoamide VE008400View CAS 2469244-33-3
Anastrozole Anastrozole Monoamide Mononitrile Impurity VL2490002View CAS 1338800-82-0
Anastrozole Anastrozole-D12 DVE00157View CAS 120512-32-5

Anastrozole Related Compound

It works by reducing estrogen hormone levels in your body. It is primarily administered to women who have gone through menopause and have hormone-dependent breast cancer.



What class does anastrozole belong to?

Anastrozole belongs to a class of drugs known as nonsteroidal aromatase inhibitors. It works by reducing the quantity of estrogen produced by the body. Many forms of breast cancer cells that require estrogen to proliferate can be slowed or stopped by this.

What is the use of anastrozole in fertility?

Anastrazole inhibits aromatase activity, resulting in increased testosterone levels and reduced estrogen levels. Anastrozole can also increase FSH and LH levels by blocking the negative feedback that estradiol has on the pituitary gland.

What is the drug anastrozole used for?

Anastrozole is a medication that is used to treat early hormone receptor-positive breast cancer. It is also used as the first-line therapy for advanced or metastatic (cancer that has spread) hormone receptor-positive or hormone receptor-unknown breast cancer.


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1027160-12-8: Anastrozole EP Impurity D

1027160-12-8: Anastrozole EP Impurity D
Catalogue No.




Molecular Formula


Molecular Weight


Parent drug



3, 5-Bis(2-cyanoprop-2-yl)bromobenzyl bromide


Anastrozole Dibromo Impurity


Cuzick, Jack, et al. “Anastrozole for Prevention of Breast Cancer in High-Risk Postmenopausal Women (IBIS-II): An International, Double-Blind, Randomised Placebo-Controlled Trial.” Lancet (London, England), vol. 383, no. 9922, 2014, pp. 1041–8,, 10.1016/S0140-6736(13)62292-8. Accessed 21 Nov. 2019.




Anastrozole EP Impurity D

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