Azasetron Impurities

Azasetron is an antiemetic that functions as a 5-HT3 receptor antagonist. It is used to treat nausea and vomiting caused by cancer treatment.

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Azasetron Impurity 1 Azasetron

Azasetron Impurity 1

VL6070002 123040-79-9

Azasetron Related Compound

And also used for Arrhythmias (tropisetron), irritable bowel syndrome (ramosetron), and schizophrenia.

References

  • Briggs, Clark A., and M. Gopalakrishnan. Ion Channels – Ligand Gated. Jan. 2007, pp. 877–918, https://doi.org/10.1016/b0-08-045044-x/00067-5. Accessed 6 Aug. 2023.
  • “Anzemet (Dolasetron) Dosing, Indications, Interactions, Adverse Effects, and More.” Medscape.com, 13 Apr. 2023, reference.medscape.com/drug/anzemet-dolasetron-342046. Accessed 6 Aug. 2023.

FAQ

What class does Azasetron belong to?

5HT3 antagonists are commonly used as antiemetics after surgery and during chemotherapy.

What is the use of azasetron?

Used to reduce nausea and vomiting produced by cancer treatment. Dolasetron belongs to a family of drugs known as serotonin 5-HT3 receptor antagonists. It acts by inhibiting the function of serotonin, a naturally occurring chemical that causes nausea and vomiting.

What is the mechanism of action of azasetron?

Is a 5-HT3 serotonin receptor antagonist used to alleviate nausea and vomiting after chemotherapy. Its primary function is to decrease the activity of the vagus nerve, which stimulates the vomiting center in the medulla oblongata.