Tenofovir Impurities

Tenofovir is a medication used to treat human immunodeficiency virus infections (HIV).

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Parent Drug Name Name of Impurity Catalogue No.
Tenofovir Tenofovir (MOC-POC-PMPA) VL470019View CAS 1246812-43-0
Tenofovir Tenofovir (S)-Enantiomer VL470009View CAS 1432630-26-6
Tenofovir Tenofovir 9-Allyl Impurity VE006716View CAS 4121-39-5
Tenofovir Tenofovir Adenine impurity / Adenosine EP Impurity A VL470025View CAS 73-24-5
Tenofovir Tenofovir Alafenamide Fumarate VE009339View CAS 379270-38-9
Tenofovir Tenofovir Diethyl Ester (S)-Isomer VL470012View CAS 1217630-57-3
Tenofovir Tenofovir Dimer VE008551View CAS 1607007-18-0
Tenofovir Tenofovir Disoproxil Desmethyl VL470034View CAS 365417-53-4
Tenofovir Tenofovir Disoproxil Dimer Impurity VL470015View CAS 1093279-76-5
Tenofovir Tenofovir Disoproxil Fumarate VE006981View CAS 202138-50-9
Tenofovir Tenofovir Disoproxil Fumarate IP Impurity A VL470024View CAS 211364-69-1
Tenofovir Tenofovir Disoproxil Fumarate IP Impurity D VL470022View CAS 1422284-15-8
Tenofovir Tenofovir Disoproxil Fumarate IP Impurity E VL470002View CAS 1244022-56-7
Tenofovir Tenofovir Disoproxil Fumarate IP Impurity G (Free Base) VE008089View CAS 1280130-08-6
Tenofovir Tenofovir Disoproxil Fumarate IP Impurity M VL470018View CAS 1422284-16-9
Tenofovir Tenofovir Disoproxil Fumarate Impurity (N6-CH2OH-POC PMPA) VE0014019View CAS 1244022-55-6
Tenofovir Tenofovir Disoproxil Isopropoxycarbonyl Impurity VE008090View CAS 1244022-54-5
Tenofovir Tenofovir Disoproxil Related Compound B VL470021View CAS 4121-40-8
Tenofovir Tenofovir IPR Impurity VL470003View CAS 1246812-40-7
Tenofovir Tenofovir Isopropyl Impurity VL470031View CAS 1346597-36-1
Tenofovir Tenofovir ME Impurity VL470004View
Tenofovir Tenofovir Mixed Dimer VL470001View CAS 1093279-77-6
Tenofovir Tenofovir Mono POC Dimer VL470014View CAS 1962114-92-6
Tenofovir Tenofovir Monoester VL470026View
Tenofovir Tenofovir Monoethyl Ester VL470011View CAS 1796545-19-1
Tenofovir Tenofovir Monoisoproxil Ethoxy Impurity VE008091View CAS 1796539-92-8
Tenofovir Tenofovir NPOC POC PMPA VL470008View CAS 1217542-13-6
Tenofovir Tenofovir Phenyl PMPA VE008097View CAS 379270-35-6
Tenofovir Tenofovir Related Compound 4 VE008096View CAS 851456-00-3
Tenofovir 6N-Hydroxymethyl Tenofovir Disoproxil VE0014020View CAS 1244022-53-4
Tenofovir (R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine VE0010429View CAS 180587-75-1

Tenofovir Related Compound

The virus that causes acquired immunodeficiency syndrome is HIV (AIDS).



What is the therapeutic effect of tenofovir?

Tenofovir-diphosphate inhibits HIV replication by competing for incorporation into DNA during HIV transcription with the natural substrate deoxyadenosine 5′-triphosphate. Tenofovir-diphosphate prevents HBV replication by blocking HBV polymerase.

Can tenofovir be used to treat hepatitis B?

Tenofovir disoproxil fumarate, tenofovir alafenamide, and adefovir are nucleotide reverse transcriptase inhibitors (NRTIs) used to treat chronic HBV infection. Tenofovir, on the other hand, has mostly replaced adefovir because it is more powerful.

Do NRTIs include tenofovir?

Tenofovir, an ester prodrug of the nucleotide reverse transcriptase inhibitor (NRTI) tenofovir, is used to treat HIV infection in combination with other antiretroviral drugs.


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1093279-76-5: Tenofovir Disoproxil Dimer Impurity

1093279-76-5: Tenofovir Disoproxil Dimer Impurity
Catalogue No.




Molecular Formula


Molecular Weight


Parent drug



5-[[(1R)-2-[6-[[[[9-[(2R)-2, 11-Dimethyl-5-[[[(1-methylethoxy)carbonyl]oxy]methoxy]-5-oxido-9-oxo-3, 6, 8, 10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]-2, 4, 6, 8-tetraoxa-5-phosphanonanedioic Acid 1, 9-Bis(1-methylethyl) Ester 5-Oxide;




Sci-Hub, Process Improvements for the Manufacture of Tenofovir Disoproxil Fumarate at Commercial Scale, 10.1021/op1001337. (2022). Retrieved January 24, 2022, from Sci-hub.ee website: https://sci-hub.ee/10.1021/op1001337




Tenofovir Disoproxil Dimer Impurity

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