Tioconazole is an imidazole-class antifungal medication used to treat fungal and yeast infections. It works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, leading to cell death.
Tioconazole is commonly used in topical formulations—creams or ointments—and is especially effective for:
• Vaginal yeast infections (as a single-dose intravaginal ointment)
• Skin infections such as athlete’s foot, jock itch, and ringworm
It is marketed under the brand names Trosyd and Gyno-Trosyd, originally by Pfizer, then Johnson & Johnson, and now by Kenvue.

Parent: Tioconazole
Parent: Tioconazole
Parent: Tioconazole
Parent: Tioconazole
Impurities in Tioconazole may arise during chemical synthesis, formulation, or storage. Regulatory authorities (FDA, EMA, ICH) require strict limits on impurities to ensure drug safety and stability.
Process-Related Impurities
Degradation Impurities
Elemental Impurities
Analytical Techniques for Impurity Detection
Tioconazole is used to treat fungal and yeast infections, especially: