Phenylephrine EP Impurity C (HCl Salt) | CAS 94240-17-2 | é uma impureza relacionada à síntese do cloridrato de fenilefrina | também denominada Phenylephrine Related Compound C (HCl salt). Caracteriza-se por massa molecular e perfil espectral distintos detectáveis por HPLC-MS e RPLC com padrões de retenção específicos; espectros NMR confirmam substituições aromáticas e agrupamentos ionizáveis. Solúvel em água e meios tamponados | apresenta estabilidade dependente de pH e temperatura | sendo formada por reações secundárias durante amidação e cloridratação. Monitoramento em controle de qualidade inclui limites de especificação | testes de degradação forçada e quantificação por método validado de HPLC | essenciais para garantir pureza e conformidade farmacopéica.
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