Cefadroxil Impurities

Cefadroxil is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for viral infections. Technically, cefadroxil is an orally active first generation cephalosporin that inhibits bacterial cell wall synthesis through high affinity binding to penicillin binding proteins resulting in bactericidal activity. It has good oral absorption, substantial renal excretion of unchanged drug, and a serum half life that supports once or twice daily dosing depending on infection severity and renal function. Clinical use targets gram positive organisms including streptococci and many staphylococci and selected gram negative enteric bacilli. Important considerations include dose adjustment in renal impairment, avoidance in patients with known severe immediate hypersensitivity to beta lactams unless allergy evaluation permits use, and monitoring for gastrointestinal adverse effects and Clostridioides difficile associated diarrhea during therapy.