Also known as 5,6-Dimethoxy-1-indanone or Donepezil Indanone is a key moiety of donepezil that is one of the most important drugs used in the treatment of Alzheimer’s disease is a nontoxic, blood-brain barrier permeable, reversible, and noncompetitive acetylcholinesterase inhibitor.
References
Mozaffarnia, Sakineh, et al. “Design, Synthesis and Biological Evaluation of 2, 3-Dihydro-5, 6-Dimethoxy-1H-Inden-1-One and Piperazinium Salt Hybrid Derivatives as HAChE and HBuChE Enzyme Inhibitors.” European Journal of Medicinal Chemistry, vol. 191, Apr. 2020, p. 112140, https://doi.org/10.1016/j.ejmech.2020.112140. ?
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