Aliskiren Hemifumarate Enantiomer (RRRR isomer) is an impurity of Aliskiren, Aliskiren is an orally active compound, it inhibits the enzyme renin which is involved in the initial and rate-limiting step of the renin-angiotensin system (RAS).it is approved for the treatment of hypertension and may be used alone.
References
Frampton, James E., and Monique P. Curran. “Aliskiren.†Drugs, vol. 67, no. 12, 2007, pp. 1767–92, https://doi.org/10.2165/00003495-200767120-00008.
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