Buspiron EP-Verunreinigung I, auch als Chlorobuspiron bezeichnet, ist eine chlorierte prozessbedingte Verunreinigung des azaspirodekanedionhaltigen Anxiolytikums Buspiron. Die CAS-Nummer 2725354-99-2 gehört zu C21H30ClN5O2 mit einer Molekülmasse von 419,95 g/mol. Das Chloratom weist auf ein halogeniertes Synthese-Nebenprodukt oder Substitutionsprodukt hin, das aus routeabhängiger Zwischenstufenchemie oder einer Nebenreaktion entstehen kann. Die analytische Trennung erfordert üblicherweise RP-HPLC mit LC-MS/MS oder hochauflösender MS-Bestätigung, während NMR die Strukturzuordnung stützen kann. Als definierte Einzelverunreinigung wird sie im Rahmen regulatorischer Verunreinigungsprofile und Spezifikationsgrenzen überwacht.
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