(R)-3-Aminopiperidindihydrochlorid, CAS 334618-23-4, ist das Hydrochloridsalz eines chiralen, gesättigten Heterocyclus mit einer primären Aminogruppe in 3-Position. Mit der Summenformel C5H14Cl2N2 und einer Molmasse von 173.08 g/mol tritt diese Verbindung häufig als prozessbedingte Verunreinigung oder synthetisches Zwischenprodukt in der Piperidinchemie auf, etwa infolge unvollständiger stereochemischer Auftrennung oder von Nebenreaktionen bei reduktiver Aminierung und Ringsynthese. Aufgrund des basischen, polaren Amincharakters erfolgt die Charakterisierung typischerweise mittels LC-MS/MS, HILIC-LC und chiraler Trennverfahren, bei Bedarf ergänzt durch GC-MS nach Derivatisierung. Der regulatorische Fokus liegt auf Herkunft der Verunreinigung und enantiomerer Integrität.
References
Petri, Antonella, et al. “Asymmetric Synthesis of a High Added Value Chiral Amine Using Immobilized o-Transaminases.” Beilstein Journal of Organic Chemistry, vol. 15, Jan. 2019, pp. 60–66, https://doi.org/10.3762/bjoc.15.6.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Immer aktiv
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Immer aktiv
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
