Rifampicina 23-O-Acetil Análogo (CAS 1416773-23-3) | conocido también como Rifampicina Impureza 3 | Impureza 9 | 23-Transacetil rifampicina o 25-Deacetyl-23-acetyl Rifampicin | es una impureza estructural derivada de la acetilación en el átomo de oxígeno del carbono 23 que puede generarse durante la síntesis o degradación de rifampicina. Su identificación y cuantificación se realizan mediante técnicas analíticas avanzadas como HPLC-UV | LC-MS y RMN para caracterizar masa | retención y patrones de fragmentación. Esta impureza se controla según guías ICH mediante optimización de condiciones de reacción | pasos de purificación y estudios de estabilidad para minimizar impactos en pureza | seguridad y eficacia del producto final.
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