Impureza Sorafenib IP Impurity B (CAS: 2514724-45-7) es una impureza relacionada con el proceso que se forma como subproducto durante la síntesis o la degradación de Sorafenib. Presenta masa molecular y patrones de fragmentación característicos detectables por LC-MS | y un perfil de retención específico en HPLC con detección UV. Su identificación requiere RMN para confirmar conectividad y espectros de masas para precisar modificaciones estructurales. La detección y cuantificación demandan métodos analíticos validados y límites de especificación definidos. El control incluye optimización de condiciones de reacción | purificación adicional y estudios de estabilidad para minimizar su presencia en materia prima.
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