La impureza 6»’-Deamino-6»’-hydroxyparomomycin II (CAS 78549-65-2) requiere control riguroso en el perfil de impurezas por su impacto potencial en la pureza y estabilidad del principio activo. Su identificación y cuantificación mediante técnicas analíticas avanzadas como LC-MS | HPLC y RMN permiten caracterizar su retención | masas y señales protonales para establecer límites y criterios de aceptación. La evaluación forense de esta impureza incluye estudio de degradación | cromatografía de referencia y validación de métodos para asegurar trazabilidad | cumplimiento regulatorio y prevención de efectos sobre la eficacia y seguridad del lote final.
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