(2R-cis)-4-Methyl-2-piperidinecarboxylic Acid Ethyl Este Ethyl (2R,4S)-4-Methylpipecolate Argatroban Impurity 8 (2S,4R)-4-methyl-2-piperidinecarboxylate Argatroban Related Compound 1Argatroban Related Compound 1 (Ethyl (2R,4S)-4 Methylpipecolate) Argatroban Impurity 40 (Ethyl (2R,4S)-4 Methylpipecolate)
Descripción
Impureza Argatroban 40 (CAS 79199-61-4) | conocida también como Ethyl (2R | 4S)-4-metilpipecolato | Argatroban Related Compound 1 o (2S | 4R)-4-metil-2-piperidinecarboxilato | es un subproducto estereoespecífico del proceso sintético de argatroban. Presenta un anillo pipecolato sustituido en posición 4 y un éster etílico | con centros quirales en 2 y 4 | lo que exige control estereoquímico durante la síntesis. Su presencia impacta en la pureza del principio activo y requiere cuantificación y caracterización mediante HPLC con columna quiral | LC-MS y RMN para identificación de isómeros y confirmación de masa. Se suministra como estándar de referencia para el desarrollo analítico y cumplimiento de especificaciones regulatorias.
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