Capecitabine 3-Methylbutyloxy Impurity; [1-(5-Deoxy-?-D-ribofuranosyl)-5-fluoro-1, 2-dihydro-2-oxo-4-pyrimidinyl]-carbamic Acid 3-Methylbutyl Ester; 5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine; Capecitabine EP Impurity E
Descripción
Capecitabine EP Impurity E (CAS 162204-30-0) es una impureza relacionada observada en procesos de síntesis de capecitabina | caracterizada como un éster 3-metilbutilo del nucleósido 5′-desoxi-5-fluoro con el grupo isopentyloxycarbonyl. También referida como Capecitabine 3-Methylbutyloxy Impurity o 5′-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine | requiere identificación y cuantificación rigurosa por técnicas analíticas como HPLC con detección UV | LC-MS y RMN para confirmar estructura y masa. El control de lote | límites de especificación y estudios de degradación son esenciales para la seguridad y la calidad del producto final | y para optimizar procedimientos de purificación y control de procesos.
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