Cephalexin S-Sulfoxide es una impureza oxidativa resultante de la oxidación del átomo de azufre presente en la cadena lateral del núcleo cepém. Su presencia indica degradación por exposición a agentes oxidantes | calor o almacenamiento inadecuado y puede alterar la pureza | estabilidad y perfil de seguridad del API. Se monitoriza rutinariamente mediante HPLC con detección UV y confirmación por LC-MS y RMN para identificar la masa y el estado de oxidación. El control se logra mediante optimización del proceso | uso de atmósferas inertes | antioxidantes y pruebas de estabilidad acelerada para garantizar cumplimiento de especificaciones.
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