Ubicación del inventario

New Jersey, USA
Czech Republic, EU
Mumbai, India

* Sujeto a disponibilidad

Documentation

Descargar MSDS

Descargar COA de muestra

Incluye: HPLC, MASS/LC-MS, RMN de 1H, FT-IR, potencia, informe de elucidación estructural (SER) y datos analíticos adicionales según el producto.

120014-30-4Donepezil EP Impurity A

● En Stock

Número de catálogo:	VE006102
N.º CAS:	120014-30-4
Fórmula mol.::	C17H23NO3
Peso mol.::	289.4 g/mol

Solicitar cotización

Añadir a la lista de RFQ

Información adicional sobre el CAS 120014-30-4

Fármaco de origen

Donepezil

Nombre IUPAC

5, 6-Dimethoxy-2-(piperidin-4-ylmethyl) indan-1-one

Sinónimos farmacopeicos

Desbenzyl Donepezil

Otros sinónimos

5,6-dimethoxy-2-(piperidin-4-yl)methylene-indan-1-one; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-; 5,6-dimethoxy-2-(piperidin-4-ylmethyl)-2,3-dihydroinden-1-one; 5,6-Dimethoxy-2-piperidin-4-ylmethyl-indan-1-one; 4-((5,6-Dimethoxy-1-oxoindan-2-yl)methyl)piperidine;(acetyloxy)tributyl-Stannane;

SMILES

O=C1C(CC2CCNCC2)CC3=C1C=C(OC)C(OC)=C3

InChI

InChI=1S/C24H20N6O3/c1-2-33-23(31)19-8-5-9-20-21(19)30(24(32)25-20)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,25,32)(H,26,27,28,29)

Condición de envío

Ambient Temperature

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Datos adicionales de caracterización

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

Descripción

Donepezil EP Impurity A known in pharmacopoeias as Desbenzyl Donepezil is a thoroughly characterized reference standard. It meets strict regulatory standards including those set by USP EMA JP and BP. This product is crucial for use in Abbreviated New Drug Applications (ANDA) New Drug Applications (NDA) and the commercial production of Donepezil. Additionally it comes with a detailed Structure Elucidation Report (SER) ensuring its precision and dependability for a variety of analytical uses. Also known as Desbenzyl Donepezil (free base ), it is a process-related impurity of Donepezil drug which is a specific, selective, and potent inhibitor of acetylcholinesterase an approved drug for the treatment of Alzheimer’s disease.

Referencias

Krishna Reddy, K. V. S. R., et al. “Identification and Characterization of Potential Impurities of Donepezil.” Journal of Pharmaceutical and Biomedical Analysis, vol. 35, no. 5, Sept. 2004, pp. 1047–58, https://doi.org/10.1016/j.jpba.2004.03.022.