Información adicional sobre el Met(O) 8-Teriparatide
Fármaco de origen
Teriparatide
Nombre IUPAC
Met(O) 8-Teriparatide
Sinónimos
N/A
Descripción
Met(O) 8-Teriparatide es una impureza oxidada del péptido teriparatida caracterizada por la oxidación del residuo metionina en la posición 8. Desde un punto de vista técnico presenta un ligero incremento de masa y cambios en la polaridad que afectan su retención cromatográfica y su respuesta en espectrometría de masas. Su presencia puede alterar el perfil de pureza | la potencia y la estabilidad del producto final | por lo que su cuantificación y control son críticos en el desarrollo farmacéutico. Se recomienda incluir criterios de aceptación específicos en especificaciones analíticas y vigilancia del perfil de impurezas durante procesos de formulación y almacenamiento.
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To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
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The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
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