La impureza N-methyl-N-((3S | 4S)-4-methyl-1-nitrosopiperidin-3-yl)-6 | 7-dihydro-5H-pyrrolo[2 | 3-d]pyrimidin-4-amine constituye un parámetro crítico en perfiles de calidad | formándose por nitrosación y reacciones secundarias durante la síntesis y el almacenamiento; presenta retos analíticos por su isomería y polaridad | por lo que requiere métodos validados como HPLC con detección UV y ESI-MS y confirmación estructural por RMN. Su presencia puede afectar estabilidad y seguridad del proceso | por lo que las estrategias de control incluyen optimización de condiciones de reacción | eliminación de agentes nitrosantes y programas de monitoreo continuo para garantizar cumplimiento de especificaciones.
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To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
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![N-methyl-N-((3S,4S)-4-methyl-1-nitrosopiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine](https://veeprho.com/wp-content/uploads/2023/02/N-methyl-N-3S-4S-4-methyl-1-nitrosopiperidin-3-yl-6-7-dihydro-5H-pyrrolo-2-3-d-pyrimidin-4-amine-sqr.png "N-methyl-N-((3S,4S)-4-methyl-1-nitrosopiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine")
