Impureza 3-hidroxibenzaldehído (CAS 100-83-4) relevante en el control de calidad de materias primas y procesos de síntesis por su potencial impacto en la pureza final; presenta un perfil físico-químico definido que facilita su identificación por HPLC | GC-MS | RMN y espectrometría de masas | y cuya cuantificación precisa es crítica para cumplir límites de especificación y requisitos regulatorios. Esta impureza puede originarse por rutas de degradación o reacciones laterales | requiere evaluación de estabilidad y establecimiento de niveles aceptables | y se aborda mediante métodos analíticos validados | estrategias de mitigación en procesos y materiales de referencia certificados para asegurar trazabilidad.
Referencias
Kong, Byung Soo, et al. “Vasculoprotective Effects of 3-Hydroxybenzaldehyde against VSMCs Proliferation and ECs Inflammation.†PLOS ONE, edited by Maria Cristina Vinci, vol. 11, no. 3, Mar. 2016, p. e0149394, https://doi.org/10.1371/journal.pone.0149394.
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