Salcaprozate Impurity 5 | CAS 6557-85-3 | conocido también como Diethyl(6-bromohexyl)propanedioate | es una impureza halogenada presente como éster diétil con una cadena 6-bromohexil; su presencia indica rutas secundarias de alquilación o halogenación durante la síntesis y puede comprometer el perfil de pureza y la estabilidad del material | requiriendo evaluación específica de riesgo. La naturaleza bromada confiere polaridad y reactividad particulares | por lo que su identificación y cuantificación se realizan mediante HPLC con detección UV | LC-MS y confirmación por GC-MS y RMN 1H/13C. El control se consigue optimizando condiciones de reacción | estrategias de purificación y estableciendo límites analíticos apropiados para control de calidad.
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