Trazodone 4-Chloro Analog; 2-[3-(4-Phenyl-1-piperazinyl)propyl]-1, 2, 4-triazolo[4, 3-a]pyridin-3(2H)-one; Trazodone Impurity B
Descripción
Trazodone BP Impurity C (sal de HCl) | CAS 62337-66-0 | también referida como Trazodone 4-Chloro Analog | 2-[3-(4-Phenyl-1-piperazinyl)propyl]-1 | 2 | 4-triazolo[4 | 3-a]pyridin-3(2H)-one o Trazodone Impurity B | es un derivado clorado que aparece como subproducto en procesos de síntesis y purificación de trazodona. Su identificación y cuantificación mediante HPLC con detección UV y confirmación por espectrometría de masas son esenciales para asegurar cumplimiento de especificaciones. Presenta comportamiento retentivo y fragmentación característica que facilitan su separación analítica. El control de parámetros de reacción | condiciones de cloración y etapas de lavado minimiza su formación. Se recomienda establecer límites de aceptación | perfiles de estabilidad y condiciones de almacenamiento para control de la calidad.
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![2-nitroso-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one](https://veeprho.com/wp-content/uploads/2023/12/VE0017088-2-nitroso-124triazolo43-apyridin-32H-one-1.png "2-nitroso-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one")
