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944-73-0Theophylline EP Impurity E
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| Catalogue No.: | VE006974 |
|---|---|
| CAS No.: | 944-73-0 |
| Mol. Formula: | C7H8N4O3 |
| Mol. Weight: | 196.16 g/mol |
Additional information on CAS 944-73-0
Parent drug
TheophyllineIUPAC Name
1, 3-Dimethyl-7, 9-dihydro-1H-purine-2, 6, 8(3H)-trionePharmacopoeial Synonyms
N/AOther Synonyms
1,3-Dimethyluric acid; OxytheophyllineSmiles
O=C(N1C)N(C)C2=C(NC(N2)=O)C1=OInChI
InChI=1S/C7H8N4O3/c1-10-4-3(8-6(13)9-4)5(12)11(2)7(10)14/h1-2H3,(H2,8,9,13)Description
Also known as Oxytheophylline, it is the major metabolite of theophylline that is used in the electrochemical and enzymic oxidation of a dialkyl purine. Theophylline is used to manage chronic asthma and for several years was approved as a first-line agent for the treatment of chronic asthma.References
Yoon, Yeomin, et al. “Associations between CYP2E1 Promoter Polymorphisms and Plasma 1, 3-Dimethyluric Acid/Theophylline Ratios.†European Journal of Clinical Pharmacology, vol. 62, no. 8, July 2006, pp. 627–31, https://doi.org/10.1007/s00228-006-0165-4. ?Goyal, Rajendra N., and Naveen K. Singhal. “Comparison of Electrochemical and Enzymic Oxidation of 1, 3-Dimethyluric Acid.†Bioelectrochemistry and Bioenergetics, vol. 44, no. 2, Jan. 1998, pp. 201–8, https://doi.org/10.1016/s0302-4598(97)00083-4Request a Quote
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