Salbutamol EP Impurity C
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18910-68-4Salbutamol EP Impurity C

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Catalogue No.:VL1880001
CAS No.:18910-68-4
Mol. Formula:C13H21NO2
Mol. Weight:223.31 g/mol

Additional information on CAS 18910-68-4

Parent drug

Salbutamol

IUPAC Name

(1RS)-2-[(1,1-dimethylethyl)amino]-1-(4-hydroxy-3-methylphenyl)ethanol

Pharmacopoeial Synonyms

Salbutamol BP Impurity C; Levalbuterol Related Compound B; Albuterol Related Compound A

Other Synonyms

Salbutamol Deshydroxy Impurity ; 3-Dehydroxy Salbutamol

Smiles

CC1=CC(C(O)CNC(C)(C)C)=CC=C1O

InChI

InChI=1S/C13H21NO2/c1-9-7-10(5-6-11(9)15)12(16)8-14-13(2,3)4/h5-7,12,14-16H,8H2,1-4H3

Description

Salbutamol EP Impurity C, also known as Salbutamol BP Impurity C; Levalbuterol Related Compound B; Albuterol Related Compound A, in various pharmacopoeias, is a highly characterized standard. It meets strict regulatory requirements set by USP, EMA, JP, and BP, making it a crucial component in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Salbutamol/ Levalbuterol. Salbutamol EP Impurity C / Salbutamol BP Impurity C / Albuterol Related Compound A / Levalbuterol Related Compound B / Salbutamol Deshydroxy Impurity (CAS No: 18910-68-4) or 4-(2-(tert-butylamino)-1-hydroxyethyl)-2-methylphenol, is formulated as a racemic mixture of the R- and S-isomers and a moderately selective beta(2)-receptor agonist that is used to treat asthma, bronchitis, COPD.

References

Lavorini, Federico, et al. Clinical and Functional Responses to Salbutamol Inhaled via Different Devices in Asthmatic Patients with Induced Bronchoconstriction.” British Journal of Clinical Pharmacology, vol. 58, no. 5, Nov. 2004, pp. 512–20, https://doi.org/10.1111/j.1365-2125.2004.02185.x.

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