145513-93-5: (2S,3aS,7aR)-Octahydro-1H-indole-2-carboxylic Acid
It is one of impurity present in Perindopril, Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme, and this is responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure. renal blood pressure reduced renin is released from the granular cells of the juxtaglomerular apparatus in the kidneys. Perindopril is used to treat mild to moderate essential hypertension, and moderate congestive heart failure and reduce cardiovascular risk and coronary disease.
Additional information on CAS 145513-93-5
VE009486
145513-93-5
C9H15NO2
169.22 g/mol
Perindopril
(2S, 3aS, 7aR)-octahydro-1H-indole-2-carboxylic acid
N/A
Hodzic, E., Pecar, E., Dzubur, A., Smajic, E., Hondo, Z., Delic, D., & Rustempasic, E. (2020). Efficacy and Safety of Perindopril in Patients with Essential Hypertension. Materia Socio Medica, 32(1), 4. https://doi.org/10.5455/msm.2020.32.4-9
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