![1,8-Diazabicyclo[5.4.0]undec-7-ene](https://veeprho.com/wp-content/uploads/2022/07/1-8-Diazabicyclo5B5.4.05Dundec-7-ene-sqr.png "1,8-Diazabicyclo[5.4.0]undec-7-ene")
100% accuracy
of data
of data
24/7 scientific
support
support
0% tolerance in
quality of product
quality of product
Stock Locations
- New Jersey, USA
- Czech Republic, EU
- Mumbai, India
* Stock subject to availability.
Documentation
Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.
6674-22-21,8-Diazabicyclo[5.4.0]undec-7-ene
● In Stock
| Catalogue No.: | VE008082 |
|---|---|
| CAS No.: | 6674-22-2 |
| Mol. Formula: | C9H16N2 |
| Mol. Weight: | 152.24 g/mol |
Additional information on CAS 6674-22-2
Parent drug
TofacitinibIUPAC Name
2, 3, 4, 6, 7, 8, 9, 10-octahydropyrimido[1, 2-a]azepinePharmacopoeial Synonyms
N/AOther Synonyms
1,8-Diaza-7-bicyclo[5.4.0]undecene; 1,8-Diazabicyclo[5.4.0]undecene-7Smiles
C2CCC1=NCCCN1CC2InChI
InChI=1S/C9H16N2/c1-2-5-9-10-6-4-8-11(9)7-3-1/h1-8H2Shipping Condition
Ambient TemperatureCharacterization Data (Included)
HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).Additional Characterization Data
QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.Description
1,8-Diazabicyclo[5.4.0]undec-7-ene (CAS No: 6674-22-2) shows excellent catalytic activity in the Baylis–Hillman reaction. DBU is studied as a promoter for the aza-Michael reaction mainly used for constructing b-aminocarbonyl compounds. B-aminocarbonyl compounds are utilized as building blocks for various nitrogen-containing biologically essential compounds.References
Yeom, Chang-Eun, et al. “1, 8-Diazabicyclo[5.4.0]Undec-7-Ene (DBU)-Promoted Efficient and Versatile Aza-Michael Addition.” Tetrahedron, vol. 63, no. 4, Jan. 2007, pp. 904–9, https://doi.org/10.1016/j.tet.2006.11.037. ?Request a Quote
"*" indicates required fields
Other products related to Tofacitinib impurities
Impurity structure
Parent Drug Name
CAS No.
Name of Impurity
Catalog No.
![N-methyl-N-((3S,4S)-4-methyl-1-nitrosopiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine](https://veeprho.com/wp-content/uploads/2023/02/N-methyl-N-3S-4S-4-methyl-1-nitrosopiperidin-3-yl-6-7-dihydro-5H-pyrrolo-2-3-d-pyrimidin-4-amine.png "N-methyl-N-((3S,4S)-4-methyl-1-nitrosopiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine")
Tofacitinib
CAS No. N/A
N-methyl-N-((3S,4S)-4-methyl-1-nitrosopiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine
Cat No. VE0011034
![N-methyl-N-((3S,4S)-4-methyl-1-nitrosopiperidin-3-yl)-7-nitroso-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine](https://veeprho.com/wp-content/uploads/2023/02/N-methyl-N-3S-4S-4-methyl-1-nitrosopiperidin-3-yl-7-nitroso-6-7-dihydro-5H-pyrrolo-2-3-d-pyrimidin-4-amine.png "N-methyl-N-((3S,4S)-4-methyl-1-nitrosopiperidin-3-yl)-7-nitroso-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine")
Tofacitinib
CAS No. N/A
Cat No. VE0011036
![4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine](https://veeprho.com/wp-content/uploads/2022/08/4-chloro-6-7-dihydro-5H-pyrrolo-2-3-d-pyrimidine.png "4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine")
