171596-42-2: (1S,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate

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It is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy,By promoting sexual stimulation-dependent smooth muscle relaxation in the penis, tadalafil treats erectile dysfunction by enabling the corpus cavernosum to fill with blood and produce an erection. Vasodilation in PAH, which lowers blood pressure in the pulmonary arteries, is facilitated by smooth muscle relaxation in the pulmonary vasculature.

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Additional information on CAS 171596-42-2

Catalogue No. VE009039
CAS No. 171596-42-2
Molecular Formula C20H18N2O4
Molecular Weight 350.37 g/mol
Parent drug Tadalafil
IUPAC Name (1S, 3R)-Methyl 1-(benzo[d][1, 3]dioxol-5-yl)-2, 3, 4, 9-tetrahydro-1H-pyrido[3, 4-b]indole-3-carboxylate
Synonyms N/A
Smiles COC(=O)C1CC2=C(C(N1)C3=CC4=C(C=C3)OCO4)NC5=CC=CC=C25
References Gong, Binbin, et al. “Direct Comparison of Tadalafil with Sildenafil for the Treatment of Erectile Dysfunction: A Systematic Review and Meta-Analysis.” International Urology and Nephrology, vol. 49, no. 10, July 2017, pp. 1731–40, https://doi.org/10.1007/s11255-017-1644-5. ‌
Status In-stock

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171596-42-2: (1S,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate

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