| Parent Drug Name | Name of Impurity | Catalogue No. | |
|---|---|---|---|
| Tadalafil | Tadalafil (1S-cis) Methyl Ester Impurity | VE000013 | View CAS 171596-43-3 |
| Tadalafil | Tadalafil Chloroacetyl Impurity | VL300009 | View |
| Tadalafil | Tadalafil EP Impurity A | VL300003 | View CAS 171596-27-3 |
| Tadalafil | Tadalafil EP Impurity B | VL300008 | View CAS 629652-72-8 |
| Tadalafil | Tadalafil EP Impurity C | VL300002 | View CAS 171596-28-4 |
| Tadalafil | Tadalafil EP Impurity F | VE0011467 | View CAS 2747958-44-5 |
| Tadalafil | Tadalafil Impurity II | VL300006 | View |
| Tadalafil | Tadalafil In House Impurity A | VL300007 | View CAS 120-57-0 |
| Tadalafil | Tadalafil N-Desmethyl N-Amino | VE007823 | View CAS 385769-84-6 |
| Tadalafil | Tadalafil N-Methyl | VL300004 | View CAS 477970-21-1 |
| Tadalafil | Tadalafil N-Oxide | VL300005 | View |
| Tadalafil | 1, 3-Benzodioxole-5-glycolic Acid | VE008624 | View CAS 27738-46-1 |
| Tadalafil | (1R, 3S)-Methyl 1-(benzo[d][1, 3]dioxol-5-yl)-2, 3, 4, 9-tetrahydro-1H-pyrido[3, 4-b]indole-3-carboxylate | VE009040 | View CAS 171596-44-4 |
| Tadalafil | (1R, 3S)-Methyl 1-(benzo[d][1, 3]dioxol-5-yl)-2-(2-chloroacetyl)-2, 3, 4, 9-tetrahydro-1H-pyrido[3, 4-b]indole-3-carboxylate | VE009038 | View CAS 629652-44-4 |
| Tadalafil | (1S, 3R)-Methyl 1-(benzo[d][1, 3]dioxol-5-yl)-2, 3, 4, 9-tetrahydro-1H-pyrido[3, 4-b]indole-3-carboxylate | VE009039 | View CAS 171596-42-2 |
| Tadalafil | (1S, 3R)-Methyl 1-(benzo[d][1, 3]dioxol-5-yl)-2-(2-chloroacetyl)-2, 3, 4, 9-tetrahydro-1H-pyrido[3, 4-b]indole-3-carboxylate | VE009037 | View CAS 629652-40-0 |
| Tadalafil | (1S, 3S)-Methyl 1-(benzo[d][1, 3]dioxol-5-yl)-2-(2-chloroacetyl)-2, 3, 4, 9-tetrahydro-1H-pyrido[3, 4-b]indole-3-carboxylate | VE009056 | View CAS 629652-42-2 |
Tadalafil Related Compound
Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or maintain an erection) and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) in adult men, including difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency.
References
- “Tadalafil: MedlinePlus Drug Information.” Medlineplus.gov, 2022, medlineplus.gov/druginfo/meds/a604008.html#:~:text=Tadalafil%20is%20in%20a%20class,the%20penis%20during%20sexual%20stimulation. Accessed 2 Mar. 2023.
- Grossman, Ehud. “The Role of Tadalafil in Treated Hypertensive Patients with Erectile Dysfunction.” The Journal of Clinical Hypertension, vol. 24, no. 2, Jan. 2022, pp. 182–83, https://doi.org/10.1111/jch.14434. Accessed 2 Mar. 2023.
- “How Long Does Tadalafil Last? | Hims.” Hims, 2021, www.forhims.com/blog/how-long-does-tadalafil-last#:~:text=Tadalafil%20differs%20from%20other%20PDE5,the%20National%20Library%20of%20Medicine. Accessed 2 Mar. 2023.
FAQ
What is the therapeutic class of tadalafil?
Tadalafil is part of a class of drugs known as phosphodiesterase (PDE) inhibitors. It works by boosting blood flow to the penis during sexual stimulation to treat erectile dysfunction.
Does tadalafil lower blood pressure?
Tadalafil at a low dose (5 mg daily) can enhance blood pressure regulation and erectile function. The fact that PDE5 inhibitors can decrease blood pressure while also improving erectile function implies that reducing blood pressure does not cause ED and that it is most likely caused by antihypertensive medicines.
How long does tadalafil stay effective?
Tadalafil differs from other PDE5 inhibitors in that it has a much longer duration of action. Unlike Viagra, which only works for a few hours after it is taken, Tadalafil can be effective for up to 36 hours after a single dose.
