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376592-93-7Eltrombopag Impurity 10

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Catalogue No.:	VE0014747
CAS No.:	376592-93-7
Mol. Formula:	C13H11NO3
Mol. Weight:	229.24 g/mol

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Additional information on CAS 376592-93-7

Parent drug

Eltrombopag

IUPAC Name

3′-amino-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid

Pharmacopeial Synonyms

N/A

Synonyms

Eltrombopag Amino Impurity; 3-(3-amino-2-hydroxyphenyl)benzoic acid; 3-amino-2-hydroxybiphenyl-3′-carboxylic acid

Smiles

O=C(C1=CC(C2=CC=CC(N)=C2O)=CC=C1)O

InChI

InChI=1S/C13H11NO3/c14-11-6-2-5-10(12(11)15)8-3-1-4-9(7-8)13(16)17/h1-7,15H,14H2,(H,16,17)

Shipping Condition

Ambient Temperature

Description

Eltrombopag Impurity 10, also designated Eltrombopag Amino Impurity, corresponds to CAS 376592-93-7 and is structurally defined as 3-(3-amino-2-hydroxyphenyl)benzoic acid, an anilino phenolic carboxylic acid related to the eltrombopag scaffold. With molecular formula C13H11NO3 and molecular weight 229.24 g/mol, it represents a likely synthetic intermediate carryover or minor process-related byproduct arising from incomplete aryl coupling or amination steps. Its aromatic amino and phenolic functionalities can complicate chromatographic resolution and support oxidative transformation pathways. Trace characterization typically relies on LC-MS/MS, LC-HRMS, and, when needed, NMR-assisted structure confirmation; UV detection alone is usually insufficient for definitive assignment.