7369-69-9: 4-Chloro-10H-phenothiazine

Also known as 4-Chlorophenothiazine it is an impurity present in Prochlorperazine, Prochlorperazine is an antipsychotic agent, Prochlorperazine was shown to inhibit histaminergic, cholinergic, and alpha-1 adrenergic receptors, The blockade of alpha-1 adrenergic receptors may result in sedation, muscle relaxation, and hypotension, which used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting.

Additional information on CAS 7369-69-9

Catalogue No.

VE008516

CAS No.

7369-69-9

Molecular Formula

C12H8ClNS

Molecular Weight

233.72 g/mol

Parent drug

Prochlorperazine

IUPAC Name

4-Chloro-10H-phenothiazine

Synonyms

4-Chlorophenothiazine

References

"Wu, C.-H., Bai, L.-Y., Tsai, M.-H., Chu, P.-C., Chiu, C.-F., Chen, M. Y., … Weng, J.-R. (2016). Pharmacological exploitation of the phenothiazine antipsychotics to develop novel antitumor agents–A drug repurposing strategy. Scientific Reports, 6(1). https://doi.org/10.1038/srep27540 ‌"

Status

In-stock