Alogliptin Impurity 12 (CAS No: 2089611-85-6) or (R)-2-((3-methyl-2,4-dioxo-6-(piperidin-3-ylamino)-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile, Alogliptin Impurity 12 is an impurity of Alogliptin, its lower blood glucose by preventing the breakdown of glucagonlike peptide-1 by inhibiting DPP-4.
References
Dineen, Laura, et al. “Alogliptin (Nesina) for Adults with Type-2 Diabetes.†Pharmacy and Therapeutics, vol. 39, no. 3, 1 Mar. 2014, pp. 186–202, www.ncbi.nlm.nih.gov/pmc/articles/PMC4005122/.
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