Alogliptin Impurities

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Alogliptin Benzoate Alogliptin

Alogliptin Benzoate

VL5900001 850649-62-6
Alogliptin Benzoate Dimer Impurity Alogliptin

Alogliptin Benzoate Dimer Impurity

VL5900040 1268836-55-0
Alogliptin Benzoate S-Isomer (HCl Salt) Alogliptin

Alogliptin Benzoate S-Isomer (HCl Salt)

VE009388 N/A
Alogliptin Dimer Impurity Alogliptin

Alogliptin Dimer Impurity

VE009676 N/A
Alogliptin Hydroxy Impurity Alogliptin

Alogliptin Hydroxy Impurity

VE007844 N/A
Alogliptin Impurity 1 Alogliptin

Alogliptin Impurity 1

VL5900022 2468009-93-8
Alogliptin Impurity 11 Alogliptin

Alogliptin Impurity 11

VL5900005 1618644-32-8
Alogliptin Impurity 12 Alogliptin

Alogliptin Impurity 12

VL5900006 2089611-85-6
Alogliptin Impurity 13 Alogliptin

Alogliptin Impurity 13

VL5900007 865758-98-1
Alogliptin Impurity 14 Alogliptin

Alogliptin Impurity 14

VL5900008 1820685-30-0
Alogliptin Impurity 15 Alogliptin

Alogliptin Impurity 15

VL5900010 1108731-49-2
Alogliptin Impurity 18 Alogliptin

Alogliptin Impurity 18

VL5900013 1430222-09-5
Alogliptin Impurity 2 Alogliptin

Alogliptin Impurity 2

VL5900029 N/A
Alogliptin Impurity 22 Alogliptin

Alogliptin Impurity 22

VL5900017 655-63-0
Alogliptin Impurity 23 Alogliptin

Alogliptin Impurity 23

VL5900018 1618644-29-3
Alogliptin Impurity 24 Alogliptin

Alogliptin Impurity 24

VL5900019 1430222-06-2
Alogliptin Impurity 25 Alogliptin

Alogliptin Impurity 25

VL5900020 1246610-72-9
Alogliptin Impurity 26 Alogliptin

Alogliptin Impurity 26

VL5900021 865759-10-0
Alogliptin Impurity 27 Alogliptin

Alogliptin Impurity 27

VL5900023 865758-95-8
Alogliptin Impurity 28 Alogliptin

Alogliptin Impurity 28

VL5900024 865758-96-9
Alogliptin Impurity 29 Alogliptin

Alogliptin Impurity 29

VL5900025 1246610-74-1
Alogliptin Impurity 3 Alogliptin

Alogliptin Impurity 3

VL5900030 1108732-05-3
Alogliptin Impurity 30 Alogliptin

Alogliptin Impurity 30

VL5900026 2276316-91-5
Alogliptin Impurity 33 Alogliptin

Alogliptin Impurity 33

VE0012093 2716884-59-0
Alogliptin Impurity 34 Alogliptin

Alogliptin Impurity 34

VE0012094 N/A
Alogliptin Impurity 35 Alogliptin

Alogliptin Impurity 35

VL5900043 872414-52-3
Alogliptin Impurity 37 Alogliptin

Alogliptin Impurity 37

VE0019019 125743-63-7
Alogliptin Impurity 38 Alogliptin

Alogliptin Impurity 38

VE0012105 120977-94-8
Alogliptin Impurity 39 Alogliptin

Alogliptin Impurity 39

VE0012106 6297-80-9
Alogliptin Impurity 42 Alogliptin

Alogliptin Impurity 42

VE0012108 2649425-73-8
Alogliptin Impurity 5 Alogliptin

Alogliptin Impurity 5

VL5900033 1338677-76-1
Alogliptin Impurity 51 Alogliptin

Alogliptin Impurity 51

VE0012109 184637-48-7
Alogliptin Impurity 60 Alogliptin

Alogliptin Impurity 60

VE0019296 421552-12-7
Alogliptin N-Acetylated Metabolite M-II Alogliptin

Alogliptin N-Acetylated Metabolite M-II

VL5900009 N/A
Alogliptin N-Des(cyanobenzyl) Impurity Alogliptin

Alogliptin N-Des(cyanobenzyl) Impurity

VL5900045 N/A
Alogliptin N-Formyl Carbamoyl Impurity Alogliptin

Alogliptin N-Formyl Carbamoyl Impurity

VL5900046 N/A
Alogliptin Related Compound 10 Alogliptin

Alogliptin Related Compound 10

VE0012057 N/A
Alogliptin Related Compound 16 Alogliptin

Alogliptin Related Compound 16

VE0012058 N/A
Alogliptin Related Compound 17 Alogliptin

Alogliptin Related Compound 17

VE0012059 N/A
Alogliptin Related Compound 19 Alogliptin

Alogliptin Related Compound 19

VE0012060 N/A
Alogliptin Related Compound 20 Alogliptin

Alogliptin Related Compound 20

VE0012089 N/A
Alogliptin Related Compound 30 Alogliptin

Alogliptin Related Compound 30

VE0012090 N/A
Alogliptin Related Compound 6 DiHCl Alogliptin

Alogliptin Related Compound 6 DiHCl

VE0012107 N/A
Alogliptin Related Compound 9 Alogliptin

Alogliptin Related Compound 9

VE0012056 N/A
N-Nitroso Alogliptin Benzoate Dimer Impurity Alogliptin

N-Nitroso Alogliptin Benzoate Dimer Impurity

VE0012079 N/A
N-Nitroso Alogliptin Impurity 12 Alogliptin

N-Nitroso Alogliptin Impurity 12

VE0012078 N/A
Tert-Butyl pyridin-3-ylcarbamate Alogliptin

Tert-Butyl pyridin-3-ylcarbamate

VE0012138 56700-70-0
(R)-3-Aminopiperidine Dihydrochloride Alogliptin

(R)-3-Aminopiperidine Dihydrochloride

VL5900038 334618-23-4
(S)-Alogliptin Benzoate Alogliptin

(S)-Alogliptin Benzoate

VE0012091 1638544-64-5
2-(((4-chloro-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)oxy)methyl)benzonitrile Alogliptin

2-(((4-chloro-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)oxy)methyl)benzonitrile

VE0012144 N/A

Alogliptin Related Compound

Alogliptin reduces blood sugar levels in type 2 diabetic patients combined with diet and exercise.

References

  • Alogliptin: MedlinePlus Drug Information.” Medlineplus.gov, 2016, medlineplus.gov/druginfo/meds/a613026.html#:~:text=Alogliptin%20is%20in%20a%20class,body%20to%20control%20blood%20sugar. Accessed 9 Feb. 2023.
  • Alogliptin: Uses, Interactions, Mechanism of Action | DrugBank Online.” Drugbank.com, DrugBank, 2013,go.drugbank.com/drugs/DB06203. Accessed 9 Feb. 2023. ‌

FAQ’s

What type of drug is alogliptin?

Alogliptin belongs to a family of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. It regulates blood sugar by raising the quantity of insulin in the body.

What is alogliptin used to treat?

Alogliptin is a diabetes treatment medication. Type 2 diabetes is a condition in which the body does not produce enough insulin or the insulin produced does not function correctly. This might result in elevated blood sugar levels (hyperglycaemia).

What is the mechanism of action of alogliptin?

Alogliptin inhibits DPP-4, which typically degrades the incretins glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1. ( GLP-1). DPP-4 inhibition increases the quantity of active plasma incretins, which aids in glycemic management.