119193-19-0: Alvimopan Impurity 27

Alvimopan Impurity 27 (CAS No: 119193-19-0) or [(3R,4R)-3,4-Dimethylpiperidin-4-yl]phenol is formed by degradation of alvimopan that acts peripherally by antagonist mu-opioid receptor (PAM-OR) and is utilized in the treatment of postoperative ileus.

Additional information

Catalogue No.

VE007914

CAS No.

119193-19-0

Molecular Formula

C13H19NO

Molecular Weight

205.3 g/mol

IUPAC Name

3-((3R, 4R)-3, 4-dimethylpiperidin-4-yl)phenol

Synonyms

[(3R, 4R)-3, 4-Dimethylpiperidin-4-yl]phenol

References

Baira, Shandilya Mahamuni, et al. “Identification and Structural Characterization of Hydrolytic Degradation Products of Alvimopan by LC/QTOF/MS/MS and NMR Studies.” Journal of Pharmaceutical and Biomedical Analysis, vol. 165, Feb. 2019, pp. 399–409, https://doi.org/10.1016/j.jpba.2018.12.035.

Status

In-stock