100% accuracy
of data
of data
24/7 scientific
support
support
0% tolerance in
quality of product
quality of product
Stock Locations
- New Jersey, USA
- Czech Republic, EU
- Mumbai, India
* Stock subject to availability.
Documentation
Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.
1351611-14-7Apixaban N-Formyl Impurity
● In Stock
| Catalogue No.: | VL3170016 |
|---|---|
| CAS No.: | 1351611-14-7 |
| Mol. Formula: | C26H25N5O5 |
| Mol. Weight: | 487.51 g/mol |
Additional information on CAS 1351611-14-7
Parent drug
ApixabanIUPAC Name
N-Formyl-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamidePharmacopoeial Synonyms
Apixaban Related Compound DOther Synonyms
1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, N-formyl-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]Smiles
O=C(C1=NN(C2=CC=C(OC)C=C2)C3=C1CCN(C4=CC=C(N5C(CCCC5)=O)C=C4)C3=O)NC=OInChI
InChI=1S/C26H25N5O5/c1-36-20-11-9-19(10-12-20)31-24-21(23(28-31)25(34)27-16-32)13-15-30(26(24)35)18-7-5-17(6-8-18)29-14-3-2-4-22(29)33/h5-12,16H,2-4,13-15H2,1H3,(H,27,32,34)Description
Apixaban N-Formyl Impurity, also designated Apixaban Related Compound D, is a process- and degradation-related structural variant of the factor Xa inhibitor apixaban, with CAS 1351611-14-7. Its molecular formula is C26H25N5O5 and molecular weight is 487.51 g/mol. The N-formyl functionality indicates oxidative or formylative transformation of the diazabicyclic amide nitrogen during synthesis or storage. In impurity profiling, assignment typically relies on LC-MS/MS, high-resolution LC-MS, and orthogonal HPLC methods with UV detection. Although not a classical genotoxic class, its control remains relevant under ICH impurity specifications and degradant qualification paradigms.References
Budovich, Aliaksandr, et al. “Role of Apixaban (Eliquis) in the Treatment and Prevention of Thromboembolic Disease.” Pharmacy and Therapeutics, vol. 38, no. 4, 1 Apr. 2013, pp. 206–231, www.ncbi.nlm.nih.gov/pmc/articles/PMC3684191/#b5-ptj3804206.Request a Quote
"*" indicates required fields
Other products related to Apixaban impurities
Impurity structure
Parent Drug Name
CAS No.
Name of Impurity
Catalog No.
Apixaban
CAS No. N/A
Cat No. VE0012198
Apixaban
CAS No. 27143-07-3
Cat No. VE0010298
![5-((4-(3-carbamoyl-1-(4-methoxy phenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl) (nitroso) amino) pentanoic acid](https://veeprho.com/wp-content/uploads/2023/06/5-4-3-carbamoyl-1-4-methoxy-phenyl-7-oxo-1-4-5-7-tetrahydro-6H-pyrazolo-3-4-c-pyridin-6-yl-phenyl-nitroso-amino-pentanoic20acid.png "5-((4-(3-carbamoyl-1-(4-methoxy phenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl) (nitroso) amino) pentanoic acid")
Apixaban
CAS No. 3094994-84-7
Cat No. VE0012199