Apremilast Des Oxo Impurity

Apremilast Des Oxo Impurity or N,N’-(((propane-1,3-diyldisulfonyl)bis(1-(3-ethoxy-4-methoxyphenyl)ethane-2,1-diyl))bis(1,3-dioxoisoindoline-2,4-diyl))diacetamide is an impurity of apremilast. it acts to suppress intracellular PDE-4 causing accumulation of cAMP within the cell that is used in psoriatic arthritis

Additional information

Catalogue No.

VE008011

CAS No.

N/A

Molecular Formula

C45H48N4O14S2

Molecular Weight

933.01 g/mol

IUPAC Name

N, N’-(((propane-1, 3-diyldisulfonyl)bis(1-(3-ethoxy-4-methoxyphenyl)ethane-2, 1-diyl))bis(1, 3-dioxoisoindoline-2, 4-diyl))diacetamide

References

TP Afra, et al. “Apremilast in Psoriasis and Beyond: Big Hopes on a Small Molecule.” Indian Dermatology Online Journal, vol. 10, no. 1, 2019, p. 1, http://www.idoj.in/article.asp?issn=2229-5178;year=2019;volume=10;issue=1;spage=1;epage=12;aulast=Afra;type=3, 10.4103/idoj.IDOJ_437_18. Accessed 18 Nov. 2019.

Status

In-stock