Atorvastatin Desfluoro Diol Ester Impurity
Atorvastatin Desfluoro Diol Ester Impurity or tert-Butyl (3R,5R)-3,5-dihydroxy-7-(2-isopropyl-4,5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl)heptanoate, is an HMG-CoA reductase inhibitor and lipid-lowering drug that used to reduce the myocardial infarction and stroke. it is also used as a first-line treatment option for dyslipidemia. the volume of distribution of atorvastatin is 380 L and is highly bound to plasma proteins and over 98%.
tert-Butyl (3R, 5R)-3, 5-dihydroxy-7-(2-isopropyl-4, 5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl)heptanoate
McIver, Lindsey A., and Momin S. Siddique. “Atorvastatin.” Nih.gov, StatPearls Publishing, 15 May 2022, http://www.ncbi.nlm.nih.gov/books/NBK430779/.