Atorvastatin Impurities

Atorvastatin is used along with a healthy diet to reduce blood cholesterol and triglyceride (fat) levels.

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Parent Drug Name Name of Impurity Catalogue No.
Atorvastatin ADK-1 (Atorvastatin Impurity) VL10038View CAS 124401-38-3
Atorvastatin ADK-2 (Atorvastatin Impurity) VL10039View CAS 88675-31-4
Atorvastatin Atorvastain racemic cyano side chain VE008732View
Atorvastatin Atorvastatin (3R, 5S)-Isomer (Calcium Salt) VE0012973View CAS 1312366-79-2
Atorvastatin Atorvastatin 2, 3-Anhydro lactone VL10040View CAS 442851-50-5
Atorvastatin Atorvastatin 3-Deoxy-Hept-2-Enoic Acid VL10018View
Atorvastatin Atorvastatin 3-Deoxy-Hept-2-Enoic Acid (Free Base) VE008374View CAS 1105067-93-3
Atorvastatin Atorvastatin 3-Deoxyhept-2Z-Enoic Acid (Na Salt) VE0012997View CAS 1659317-56-2
Atorvastatin Atorvastatin Acetonide Impurity VE006450View CAS 581772-29-4
Atorvastatin Atorvastatin Acetonide Methyl Ester Impurity VL10037View CAS 1553049-81-6
Atorvastatin Atorvastatin Acyl-β-D-glucuronide VE009572View CAS 463962-58-5
Atorvastatin Atorvastatin Amlodipine Dimer Or Adduct VL10041View CAS 425408-16-8
Atorvastatin Atorvastatin Calcium Impurity-J VE006263View
Atorvastatin Atorvastatin Calcium Impurity-P VE006264View
Atorvastatin Atorvastatin Dehydro Lactone (R-Isomer) VE0011077View
Atorvastatin Atorvastatin Desfluoro Diol Ester Impurity VE009397View
Atorvastatin Atorvastatin Dibromo Impurity VE008631View CAS 2514955-94-1
Atorvastatin Atorvastatin Diepoxide VE006221View CAS 887470-43-1
Atorvastatin Atorvastatin Diepoxide Calcium Salt VL10014View
Atorvastatin Atorvastatin Diepoxide Lactone Impurity VE007949View CAS 1046118-40-4
Atorvastatin Atorvastatin Diepoxy-Tetrahydropyranyl VL10036View CAS 196085-85-5
Atorvastatin Atorvastatin Diketo Amide 2-Fluoro Analog VE008630View CAS 1797905-42-0
Atorvastatin Atorvastatin EP Impurity A VE008745View CAS 433289-84-0
Atorvastatin Atorvastatin EP Impurity B (Free Base) VE009319View CAS 842103-12-2
Atorvastatin Atorvastatin EP Impurity C VE008906View CAS 693794-20-6
Atorvastatin Atorvastatin EP Impurity C (Na Salt) VE0012975View CAS 1807481-00-0
Atorvastatin Atorvastatin EP Impurity D VL10003View CAS 148146-51-4
Atorvastatin Atorvastatin EP Impurity E (Calcium Salt) VL10006View CAS 1105067-88-6
Atorvastatin Atorvastatin EP Impurity E (Free Base) VE0012984View CAS 501121-34-2
Atorvastatin Atorvastatin EP Impurity E (Na Salt) VE009244View CAS 1428118-38-0
Atorvastatin Atorvastatin EP Impurity F (Ca Salt) VL10011View CAS 1105067-87-5
Atorvastatin Atorvastatin EP Impurity F (Free Acid) VE006369View CAS 887196-24-9
Atorvastatin Atorvastatin EP Impurity F (sodium salt) VE006021View CAS 1371615-56-3
Atorvastatin Atorvastatin EP Impurity G VL10010View CAS 887196-29-4
Atorvastatin Atorvastatin EP Impurity G VE009827View CAS 887324-53-0
Atorvastatin Atorvastatin EP Impurity G (Diisopropyl Amine Salt) VE0011078View
Atorvastatin Atorvastatin EP Impurity H VL10002View CAS 125995-03-1
Atorvastatin Atorvastatin EP Impurity H-D5 DVE0055View
Atorvastatin Atorvastatin EP Impurity K VL10009View CAS 345891-62-5
Atorvastatin Atorvastatin EP Impurity O (Free Base) VE009989View CAS 887196-30-7
Atorvastatin Atorvastatin EP Impurity O (Na Salt) VL10007View CAS 1391052-00-8
Atorvastatin Atorvastatin Epoxy Tetrahydrofuran Analog VL10030View CAS 873950-19-7
Atorvastatin Atorvastatin Ethyl Ester impurity VL10024View CAS 1146977-93-6
Atorvastatin Atorvastatin FX1 Impurity VE008426View CAS 873950-18-6
Atorvastatin Atorvastatin FXA Impurity VL10023View CAS 1316291-19-6
Atorvastatin Atorvastatin FXA Impurity(Free Base) VE006545View
Atorvastatin Atorvastatin Impurity 10 VE0012991View CAS 947586-93-8
Atorvastatin Atorvastatin Impurity 21 VE0013004View CAS 125971-94-0
Atorvastatin Atorvastatin Impurity 22 VE0013008View CAS 1821498-27-4
Atorvastatin Atorvastatin Impurity 25 VE0013009View CAS 1105067-89-7
Atorvastatin Atorvastatin Impurity 28 VE0013010View CAS 1403667-07-1
Atorvastatin Atorvastatin Impurity 30 VE0013011View CAS 666714-64-3
Atorvastatin Atorvastatin Impurity 31 VE0013014View CAS 1173184-78-5
Atorvastatin Atorvastatin Impurity 34 VE0013015View
Atorvastatin Atorvastatin Impurity 46 (Na Salt) VE0013023View
Atorvastatin Atorvastatin Impurity 69 VE0012972View CAS 1116118-82-1
Atorvastatin Atorvastatin Impurity 84 (Na Salt) VE0012977View
Atorvastatin Atorvastatin Impurity 86 Pivalate VE0012978View
Atorvastatin Atorvastatin Impurity 90 VE0012979View
Atorvastatin Atorvastatin Impurity 95 VE0012981View
Atorvastatin Atorvastatin Impurity 95-D5 DVE0054View
Atorvastatin Atorvastatin Impurity Mixture CRS (Y0002310) PVE0058View
Atorvastatin Atorvastatin Isopropyl Ester VL10028View CAS 1035205-25-4
Atorvastatin Atorvastatin Lactam Lactone VL10031View CAS 906552-19-0
Atorvastatin Atorvastatin Oxirane Impurity VL10032View CAS 1246818-88-1
Atorvastatin Atorvastatin Pyrrolidone Analog VL10019View CAS 148217-40-7
Atorvastatin Atorvastatin Pyrrolidone Analog (Calcium Salt) VE0011076View
Atorvastatin Atorvastatin Pyrrolidone Analog (Free Base) VE006732View CAS 906552-18-9
Atorvastatin Atorvastatin Related Compound A VL10004View CAS 433289-83-9
Atorvastatin Atorvastatin Related Compound B VL10001View CAS 887196-25-0
Atorvastatin Atorvastatin Related Compound C VL10005View CAS 693793-53-2
Atorvastatin Atorvastatin Related Compound I VL10012View CAS 125971-95-1
Atorvastatin Atorvastatin for peak Identification A CRS PVE0017View
Atorvastatin Atorvastatin for peak identification B CRS (Y0002304) PVE0015View
Atorvastatin Atorvastatin tert-Butyl Ester VL10013View CAS 134395-00-9
Atorvastatin Atorvastatin-D5 (Ca Salt) DVE00263View CAS 222412-82-0
Atorvastatin Atorvastatin-FX1 Impurity(Na Salt) VL10021View CAS 1315629-79-8
Atorvastatin Defluoro Atorvastatin Acetonide tert-Butyl Ester VE009396View CAS 1105067-91-1
Atorvastatin Difluoro Atorvastatin Acetonide Tert-Butyl Ester VE0013017View CAS 693793-87-2
Atorvastatin Nitrosamine Impurity Of Atorvastatin VE0011042View
Atorvastatin Ortho-Hydroxy Atorvastatin-D5 Calcium Salt DVE0057View CAS 265989-47-7
Atorvastatin Ortho-Hydroxy Atorvastatin-D5 Lactone DVE0058View CAS 265989-50-2
Atorvastatin Para-Hydroxy Atorvastatin-D5 Lactone DVE0059View CAS 265989-49-9
Atorvastatin ortho-Hydroxy Atorvastatin (Ca Salt) VE0013001View CAS 265989-46-6
Atorvastatin ortho-Hydroxy Atorvastatin Lactone VE0013020View CAS 163217-74-1
Atorvastatin para-Hydroxy Atorvastatin (Ca Salt) VE0012988View CAS 265989-44-4
Atorvastatin para-Hydroxy Atorvastatin Lactone VE0013019View CAS 163217-70-7
Atorvastatin para-Hydroxy Atorvastatin-D5 (Ca Salt) DVE00264View CAS 265989-45-5
Atorvastatin 1-(2-fluorophenyl)-2-phenylethan-1-one VE009849View CAS 77294-82-7
Atorvastatin 1-(3-Fluorophenyl)-2-phenylethan-1-one VE009850View CAS 40281-50-3
Atorvastatin 10-trans-Atorvastatin Acetonide Tert-Butyl Ester VE0013006View CAS 1105067-90-0
Atorvastatin 2-Fluoro Atorvastatin (Sodium Salt) VE009131View CAS 1346598-86-4
Atorvastatin 3-Fluoro Atorvastatin (Sodium Salt) VE009130View
Atorvastatin 3-Fluro Diketoatorvastatin Derivative VE008744View
Atorvastatin 3-Oxo Atorvastatin Tert-Butyl Ester VE0012986View CAS 134394-98-2
Atorvastatin 4-Fluorobenzaldehyde VE008518View CAS 459-57-4
Atorvastatin 4-Hydroxy Atorvastatin Monosodium Salt VL10015View CAS 163217-71-8
Atorvastatin 5-(4-fluorophenyl)-2-isopropyl-1-nitroso-N, 4-diphenyl-1H-pyrrole-3-carboxamide VE0011043View
Atorvastatin 5-Oxo Atorvastatin VE008728View CAS 1391052-82-6
Atorvastatin (3R, 5R)-Atorvastatin Amide VE009318View CAS 2125501-02-0
Atorvastatin (3S, 5S)-Atorvastatin Acetonide Tert-Butyl Ester VE0012989View CAS 472967-95-6

Atorvastatin Related Compound

This medication may help avoid medical issues caused by fats obstructing blood arteries (for example, chest discomfort, heart attack, or stroke).

References

  • “Statins.” Heartuk.org.uk, 2023, www.heartuk.org.uk/getting-treatment/statins.
  • Nawrocki, James W., et al. “Reduction of LDL Cholesterol by 25% to 60% in Patients with Primary Hypercholesterolemia by Atorvastatin, a New HMG CoA Reductase Inhibitor.” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 15, no. 5, May 1995, pp. 678–82, https://doi.org/10.1161/01.atv.15.5.678.
  • Bansal, Agam B., and ManouchkatheCassagnol. “HMG-CoA Reductase Inhibitors.” Nih.gov, StatPearls Publishing, 4 July 2022.

FAQ

How effective is atorvastatin?

Often, statins have excellent results. They can lower your LDL cholesterol by about 30%, and in certain cases, large dosages can even lower it by 50%.

How rapidly does atorvastatin reduce cholesterol levels?

Atorvastatin takes effect quickly; during the first two weeks of medication, LDL cholesterol was reduced by 90% from baseline.

What is the mechanism action of atorvastatin ?

The inhibition of hepatic cholesterol synthesis causes a decrease in cholesterol in theendoplasmic reticulum, which causes the movement of sterol regulatory element bindingproteins (SREBPs) from the endoplasmic reticulum to the golgi, where they are cleaved byproteases and converted into active transcription factors.

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1035205-25-4: Atorvastatin Isopropyl Ester

1035205-25-4: Atorvastatin Isopropyl Ester
Catalogue No.

VL10028
CAS No.

1035205-25-4
Molecular Formula

C36H41FN2O5
Molecular Weight

600.72 g/mol
Parent drug

Atorvastatin
IUPAC Name

(3R, 5R)-7-[3-(Phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3, 5-dihydroxyheptanoic acid isopropyl ester
Synonyms

N/A
Smile

CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)OC(C)C)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4
References

McIver, Lindsey A., and Momin S. Siddique. Atorvastatin.” Nih.gov, StatPearls Publishing, 5 Jan. 2019, http://www.ncbi.nlm.nih.gov/books/NBK430779/. Ramkumar, Satish, et al. Statin Therapy: Review of Safety and Potential Side Effects.” Acta Cardiologica Sinica, vol. 32, no. 6, Taiwan Society of Cardiology, 2016, pp. 631–39, https://doi.org/10.6515/ACS20160611A.
Status

In-stock
ListName

Atorvastatin Isopropyl Ester
Exclusively Supplied by Veeprho

Exclusively Supplied by Veeprho

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