17431-55-9: Clindamycin BP Impurity C

Clindamycin BP Impurity C (CAS No: 17431-55-9) is a Lincomycin derivative and possesses a broad spectrum of antibacterial activities against Streptococcus pneumonia, Streptococcus pyogenes, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Neisseria gonorrhoeae. It also inhibits the chain elongation of bacterial protein by binding to 23S ribosomal RNA and consequently blocks bacterial protein synthesis.

Additional information

Catalogue No.

VE006945

CAS No.

17431-55-9

Molecular Formula

C18H34Cl2N2O5S

Molecular Weight

461.44 g/mol

IUPAC Name

Methyl 7-chloro-6, 7, 8-trideoxy-6-[[[(2S, 4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside HCl

References

Wakiyama, Yoshinari, et al. “Synthesis and Structure-Activity Relationships of Novel Lincomycin Derivatives. Part 2. Synthesis of 7(S)-7-Deoxy-7-(4-Morpholinocarbonylphenylthio)Lincomycin and Its 3-Dimensional Analysis with RRNA.” The Journal of Antibiotics, vol. 69, no. 6, Dec. 2015, pp. 428–39, https://doi.org/10.1038/ja.2015.125. ‌

Status

In-stock