4656-86-4: Dacarbazine EP Impurity A
Dacarbazine EP Impurity A (CAS No.: 4656-86-4) or Temozolomide EP Impurity E is an anticancer therapeutic agent and crystallizes in the triclinic P-1 space group. At physiological pH, temozolomide undergoes decomposition to the active compound MTIC and is a cytotoxic antitumor prodrug against malignant brain tumors.
Additional information on CAS 4656-86-4
3, 7-Dihydro-4H-imidazo[4, 5-d]-1, 2, 3-triazin-4-one
Hypoxanthine 2-Aza Impuirty / Temozolomide EP Impurity E / Dacarbazine Related Compound B / 2-Azahypoxanthine (Free Base)
?aszcz, Marta, et al. “Identification and Physicochemical Characteristics of Temozolomide Process-Related Impurities.” Molecules, vol. 18, no. 12, Dec. 2013, pp. 15344–56, https://doi.org/10.3390/molecules181215344.?
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