Dapagliflozin Dimer Impurity is an impurity present in Dapagliflozin, Dapagliflozin inhibits the sodium-glucose cotransporter 2(SGLT2) which is primarily located in the proximal tubule of the nephron1, SGLT2 facilitates 90% of glucose resorption in the kidneys and so its inhibition allows for glucose to be excreted in the urine.
References
Anderson, S. L. (2014). Dapagliflozin efficacy and safety: a perspective review. Therapeutic Advances in Drug Safety, 5(6), 242–254. https://doi.org/10.1177/2042098614551938 ‌
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