123180-72-3: Daptomycin beta-Isomer

Daptomycin Beta-Isomer (CAS No.: 123180-72-3) or 9-L-β-Aspartic acid-daptomycin is an isomer of Daptomycin which is a potent lipoprotein antibiotic targeted to gram-positive bacteria. It is potent in treating vancomycin- and methicillin-resistant Staphylococcus aureus and other antibiotic-resistant pathogenic bacteria.

Additional information

Catalogue No.

VE006900

CAS No.

123180-72-3

Molecular Formula

C72H101N17O26

Molecular Weight

1620.67 g/mol

IUPAC Name

2, 2'-((3S, 6S, 9R, 15S, 18S, 21S, 24S, 31S)-30-((R)-2-((R)-4-Amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-24-(3-aminopropyl)-6-((R)-1-carboxypropan-2-yl)-9-(hydroxymethyl)-18, 31-dimethyl-2, 5, 8, 11, 14, 17, 20, 23, 26, 29-decaoxo-1-oxa-4, 7, 10, 13, 16, 19, 22, 25, 28-nonaazacyclohentriacontane-15, 21-diyl)diacetic Acid

Synonyms

9-L-β-Aspartic acid-daptomycin

References

"Lee, Derek, et al. The Magic Bullet: Cost-Effective next Generation Cubicin *Cheaper Production of Cubicin Directed Evolution to Produce 6X His-Tagged Daptomycin in Vivo *Oral Administration of Cubicin Chitosan Encapsulation of Daptomycin to Bypass Enzymatic Liability in GI Tract. http://www.chem.cmu.edu/groups/ly/edu/pdf/Project1-Winner.pdf. Accessed 19 Oct. 2021."

Status

In-stock