Donepezil Pyridine Dehydro Impurity
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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

4803-74-1Donepezil Pyridine Dehydro Impurity

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Catalogue No.:VL173016
CAS No.:4803-74-1
Mol. Formula:C₁₇H₁₅NO₃
Mol. Weight:281.31 g/mol

Additional information on CAS 4803-74-1

Parent drug

Donepezil

IUPAC Name

5, 6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone

Synonyms

2, 3-Dihydro-5, 6-dimethoxy-2-(4-pyridinylmethylene)-1H-inden-1-one; Donepezil Impurity;

Smiles

COC1=C(C=C2C(=C1)CC(=CC3=CC=NC=C3)C2=O)OC

Description

Donepezil Pyridine Dehydro Impurity (CAS No: 4803-74-1) or 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is the intermediate formed in the synthesis of Donepezil drug which is a specific, selective, and potent inhibitor of acetylcholinesterase an approved drug for the treatment of Alzheimer’s disease

References

Krishna Reddy, K. V. S. R., et al. “Identification and Characterization of Potential Impurities of Donepezil.” Journal of Pharmaceutical and Biomedical Analysis, vol. 35, no. 5, Sept. 2004, pp. 1047–58, https://doi.org/10.1016/j.jpba.2004.03.022.

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