154154-90-2: Dorzolamide EP Impurity D

Dorzolamide EP Impurity D or Dorzolamide Related Compound D/N-Desethyl Dorzolamide (free base) or (CAS No.154154-90-2) or (4S,6S)-4-Amino-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide.Dorzolamide is a carbonic anhydrase inhibitor. It is used in the treatment of open-angle glaucoma. It has two metabolites namely N- Acetyl dorzolamide and N-diethyl-dorzolamide.

Additional information

Catalogue No.

VE007334

CAS No.

154154-90-2

Molecular Formula

C8H12N2O4S3

Molecular Weight

296.39 g/mol

IUPAC Name

(4S, 6S)-4-Amino-6-methyl-5, 6-dihydro-4H-thieno[2, 3-b]thiopyran-2-sulfonamide 7, 7-dioxide

Synonyms

Dorzolamide Related Compound D/N-Desethyl Dorzolamide (free base)

References

"Hashemi Dehaghi, Mohadeseh, et al. “Dorzolamide Loaded Niosomal Vesicles: Comparison of Passive and Remote Loading Methods.” Iranian Journal of Pharmaceutical Research : IJPR, vol. 16, no. 2, Shaheed Beheshti University of Medical Sciences, 2017, pp. 413–22, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603850/. ?Lo Faro, Alfredo Fabrizio, et al. “Development and Validation of a Fast Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry Method for Determining Carbonic Anhydrase Inhibit

Status

In-stock