1255529-24-8: Edoxaban Impurity 1
Edoxaban Impurity 1 or Edoxaban (RRR)-Isomer (CAS No. 1255529-24-8) or N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide. Factor Xa of coagulation cascade is a attractive target for anticoagulant treatment. Edoxaban is an oral direct factor Xa inhibitor. It is used in the prevention of stroke and embolism. It is used in the prevention of stroke and embolism.
Additional information on CAS 1255529-24-8
VE008119
1255529-24-8
C₂₄H₃₀ClN₇O₄S
548.06 g/mol
Edoxaban
N1-(5-chloropyridin-2-yl)-N2-((1R, 2R, 4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4, 5, 6, 7-tetrahydrothiazolo[5, 4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
Edoxaban (RRR)-Isomer
'Camm, A. John, and Henri Bounameaux. “Edoxaban.” Drugs, vol. 71, no. 12, Aug. 2011, pp. 1503–26, https://doi.org/10.2165/11595540-000000000-00000. Cuker, Adam, and Holleh Husseinzadeh. “Laboratory Measurement of the Anticoagulant Activity of Edoxaban: A Systematic Review.” Journal of Thrombosis and Thrombolysis, vol. 39, no. 3, Feb. 2015, pp. 288–94, https://doi.org/10.1007/s11239-015-1185-7. ?'
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