1255529-24-8: Edoxaban Impurity 1

Edoxaban Impurity 1 or Edoxaban (RRR)-Isomer (CAS No. 1255529-24-8) or N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide. Factor Xa of coagulation cascade is a attractive target for anticoagulant treatment. Edoxaban is an oral direct factor Xa inhibitor. It is used in the prevention of stroke and embolism. It is used in the prevention of stroke and embolism.

Additional information

Catalogue No.

VE008119

CAS No.

1255529-24-8

Molecular Formula

C₂₄H₃₀ClN₇O₄S

Molecular Weight

548.06 g/mol

IUPAC Name

N1-(5-chloropyridin-2-yl)-N2-((1R, 2R, 4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4, 5, 6, 7-tetrahydrothiazolo[5, 4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide

Synonyms

Edoxaban (RRR)-Isomer

References

'Camm, A. John, and Henri Bounameaux. “Edoxaban.” Drugs, vol. 71, no. 12, Aug. 2011, pp. 1503–26, https://doi.org/10.2165/11595540-000000000-00000. Cuker, Adam, and Holleh Husseinzadeh. “Laboratory Measurement of the Anticoagulant Activity of Edoxaban: A Systematic Review.” Journal of Thrombosis and Thrombolysis, vol. 39, no. 3, Feb. 2015, pp. 288–94, https://doi.org/10.1007/s11239-015-1185-7. ?'

Status

In-stock