145416-34-8: Emtricitabine 2-Epimer
Emtricitabine 2-Epimer or 2-epi-Emtricitabine (CAS No.145416-34-8) or 4-Amino-5-fluoro-1-[(2S,5S)-2- (hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H)-pyrimidone. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) in combination with other antiviral agents it shows activity against HIV. It is approved for use in combination therapy.
Additional information on CAS 145416-34-8
VE008051
145416-34-8
C8H10FN3O3S
247.25 g/mol
Emtricitabine
4-Amino-5-fluoro-1-[(2S, 5S)-2- (hydroxymethyl)-1, 3-oxathiolan-5-yl]-2-(1H)-pyrimidone
2-epi-Emtricitabine
'Bang, Lynne M., and Lesley J. Scott. “Emtricitabine.” Drugs, vol. 63, no. 22, 2003, pp. 2413–24, https://doi.org/10.2165/00003495-200363220-00003. ?Sax, Paul E., et al. “Coformulated Bictegravir, Emtricitabine, and Tenofovir Alafenamide versus Dolutegravir with Emtricitabine and Tenofovir Alafenamide, for Initial Treatment of HIV-1 Infection (GS-US-380–1490): A Randomised, Double-Blind, Multicentre, Phase 3, Non-Inferiority Trial.” The Lancet, vol. 390, no. 10107, Nov. 2017, pp. 2073–82, https'
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