145416-34-8: Emtricitabine 2-Epimer

Emtricitabine 2-Epimer or 2-epi-Emtricitabine (CAS No.145416-34-8) or 4-Amino-5-fluoro-1-[(2S,5S)-2- (hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H)-pyrimidone. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) in combination with other antiviral agents it shows activity against HIV. It is approved for use in combination therapy.

Additional information

Catalogue No.

VE008051

CAS No.

145416-34-8

Molecular Formula

C8H10FN3O3S

Molecular Weight

247.25 g/mol

IUPAC Name

4-Amino-5-fluoro-1-[(2S, 5S)-2- (hydroxymethyl)-1, 3-oxathiolan-5-yl]-2-(1H)-pyrimidone

Synonyms

2-epi-Emtricitabine

References

'Bang, Lynne M., and Lesley J. Scott. “Emtricitabine.” Drugs, vol. 63, no. 22, 2003, pp. 2413–24, https://doi.org/10.2165/00003495-200363220-00003. ?Sax, Paul E., et al. “Coformulated Bictegravir, Emtricitabine, and Tenofovir Alafenamide versus Dolutegravir with Emtricitabine and Tenofovir Alafenamide, for Initial Treatment of HIV-1 Infection (GS-US-380–1490): A Randomised, Double-Blind, Multicentre, Phase 3, Non-Inferiority Trial.” The Lancet, vol. 390, no. 10107, Nov. 2017, pp. 2073–82, https'

Status

In-stock