Fenofibrate EP Impurity F
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

154356-96-4Fenofibrate EP Impurity F

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Catalogue No.:VL59006
CAS No.:154356-96-4
Mol. Formula:C16H15ClO2
Mol. Weight:274.74 g/mol

Additional information on CAS 154356-96-4

Parent drug

Fenofibrate

IUPAC Name

(4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone

Pharmacopoeial Synonyms

Fenofibrate Ether

Other Synonyms

(4-chlorophenyl)-(4-propan-2-yloxyphenyl)methanone; 4-Chloro-4′-isopropoxybenzophenone

Smile

CC(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl

InChI

InChI=1S/C16H15ClO2/c1-11(2)19-15-9-5-13(6-10-15)16(18)12-3-7-14(17)8-4-12/h3-11H,1-2H3

Description

Fenofibrate EP Impurity F, also referred to in pharmacopoeias as Fenofibrate Ether, is a meticulously characterized reference standard. It adheres to stringent regulatory guidelines, including those established by USP, EMA, JP, and BP. This product plays a vital role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Fenofibrate. Furthermore, it is accompanied by a comprehensive Structure Elucidation Report (SER), ensuring its accuracy and reliability across various analytical applications. Fenofibrate EP Impurity F (CAS No.: 154356-96-4) ((4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone) is a photoproduct of the antihyperlipoproteinemic drug Fenofibrate. Fenofibrate is widely used for the treatment of dyslipidemia and activates the nuclear receptor and peroxisome proliferator-activated receptor.

References

Miranda, Miguel A., et al. “PHOTOSENSITIZATION by FENOFIBRATE. II. In Vitro PHOTOTOXICITY of the MAJOR METABOLITES.” Photochemistry and Photobiology, vol. 59, no. 2, Feb. 1994, pp. 171–74, https://doi.org/10.1111/j.1751-1097.1994.tb05018.x.

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