Stock Locations

New Jersey, USA
Czech Republic, EU
Mumbai, India

* Stock subject to availability.

Documentation

Download MSDS

Download Sample COA

Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

600-99-7Hydrocortisone EP Impurity E

● In Stock

Catalogue No.:	VE006374
CAS No.:	600-99-7
Mol. Formula:	C21H28O5
Mol. Weight:	360.44

Request a quote

Add to RFQ list

Additional information on CAS 600-99-7

Parent drug

Hydrocortisone

IUPAC Name

11β, 17, 21-Trihydroxypregna-4, 6-diene-3, 20-dione

Pharmacopoeial Synonyms

∆6-Hydrocortisone; Hydrocortisone-6-ene

Other Synonyms

6-Dehydrocortisol; (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one

Smile

O=C(CO)[C@@]1(O)CC[C@]2([H])[C@]1(C)C[C@@](O)([H])[C@@]3([H])[C@@]2([H])C=CC4=CC(CC[C@]34C)=O

InChI

InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h3-4,9,14-16,18,22,24,26H,5-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

Description

Hydrocortisone EP Impurity E also known as ∆6-Hydrocortisone , in various pharmacopoeias, is a highly characterized standard. It meets strict regulatory requirements set by USP, EMA, JP, and BP, making it a crucial component in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Hydrocortisone. Also known as ∆6-Hydrocortisone or 6-Dehydrocortisol, it is an impurity of hydrocortisone, Hydrocortisone or cortisol, and is a glucocorticoid secreted by the adrenal cortex. it is used to treat Addison’s disease or chronic adrenocortical insufficiency and in the treatment of various skin disorders.