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117678-38-3Levofloxacin EP Impurity C
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| Catalogue No.: | VL86002 |
|---|---|
| CAS No.: | 117678-38-3 |
| Mol. Formula: | C18H20FN3O5 |
| Mol. Weight: | 377.37 g/mol |
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Additional information on CAS 117678-38-3
Parent drug
LevofloxacinIUPAC Name
(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid N-oxideSynonyms
Levofloxacin N-oxide; (3S)-9-Fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-7H-Pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylic Acid; (S)-9-Fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylic Acid N-oxideDescription
Levofloxacin N-oxide, also designated Levofloxacin EP Impurity C, is the N-oxidized derivative of the fluoroquinolone scaffold, consistent with oxidative degradation of the tertiary amine nitrogen during manufacture or storage. The substance, CAS 117678-38-3, has molecular formula C18H20FN3O5 and molecular weight 377.37 g/mol. As an oxidation impurity rather than a structural genotoxic alert, it is generally evaluated within impurity profiling and stability studies. Determination typically requires reversed-phase LC-MS/MS, LC-HRMS, and orthogonal HPLC with diode-array or fluorescence detection, given its polar N-oxide functionality and chromatographic behavior.Request a Quote
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